Description
WD repeat and FYVE domain-containing protein 1 (WDFY1), also called FYVE domain-containing protein localized to endosomes 1 (FENS1), is a phosphatidylinositol 3-phosphate binding protein which contains a FYVE zinc finger domain and multiple WD-40 repeat domains. When exogenously expressed, it localizes to early endosomes. Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain